靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

KEGGPATH

hsa05231:Choline metabolism in cancer

WIKIPATH

WP1843:L1CAM interactions

WIKIPATH

WP1910:Signaling by EGFR

WIKIPATH

WP1984:Integrated Breast Cancer Pathway

WIKIPATH

WP2002:miR-targeted genes in epithelium - TarBase

WIKIPATH

WP2004:miR-targeted genes in lymphocytes - TarBase

WIKIPATH

WP2005:miR-targeted genes in muscle cell - TarBase

WIKIPATH

WP2100:Arylhydrocarbon receptor (AhR) signaling pathway

WIKIPATH

WP2261:Signaling Pathways in Glioblastoma

WIKIPATH

WP2324:AGE/RAGE pathway

WIKIPATH

WP2363:Gastric cancer network 2

WIKIPATH

WP2377:Integrated Pancreatic Cancer Pathway

WIKIPATH

WP2431:Spinal Cord Injury

WIKIPATH

WP2586:Aryl Hydrocarbon Receptor

WIKIPATH

WP2643:Nanoparticle-mediated activation of receptor signaling

WIKIPATH

WP2653:PIP3 activates AKT signaling

WIKIPATH

WP2664:Gastrin-CREB signalling pathway via PKC and MAPK

WIKIPATH

WP2780:Signaling by ERBB2

WIKIPATH

WP2781:Signaling by ERBB4

WIKIPATH

WP2804:Hair Follicle Development: Induction (Part 1 of 3)

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04020	Calcium signaling pathway
hsa04060	Cytokine-cytokine receptor interaction
hsa04066	HIF-1 signaling pathway
hsa04068	FoxO signaling pathway
hsa04144	Endocytosis
hsa04151	PI3K-Akt signaling pathway
hsa04320	Dorso-ventral axis formation
hsa04510	Focal adhesion
hsa04520	Adherens junction
hsa04540	Gap junction
hsa04810	Regulation of actin cytoskeleton
hsa04912	GnRH signaling pathway
hsa04915	Estrogen signaling pathway
hsa04921	Oxytocin signaling pathway
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05160	Hepatitis C
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05218	Melanoma
hsa05219	Bladder cancer
hsa05223	Non-small cell lung cancer
hsa05230	Central carbon metabolism in cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP437	EGF/EGFR Signaling Pathway
WP382	MAPK Signaling Pathway
WP306	Focal Adhesion
WP2873	Aryl Hydrocarbon Receptor Pathway
WP2870	Extracellular vesicle-mediated signaling in recipient cells
WP2868	TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
WP2840	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WP2828	Bladder Cancer
WP2804	Hair Follicle Development: Induction (Part 1 of 3)
WP2781	Signaling by ERBB4
WP2780	Signaling by ERBB2
WP2664	Gastrin-CREB signalling pathway via PKC and MAPK
WP2653	PIP3 activates AKT signaling
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2586	Aryl Hydrocarbon Receptor
WP2431	Spinal Cord Injury
WP2377	Integrated Pancreatic Cancer Pathway
WP2363	Gastric cancer network 2
WP2324	AGE/RAGE pathway
WP2261	Signaling Pathways in Glioblastoma
WP2100	Arylhydrocarbon receptor (AhR) signaling pathway
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP2002	miR-targeted genes in epithelium - TarBase
WP1984	Integrated Breast Cancer Pathway
WP1910	Signaling by EGFR
WP1843	L1CAM interactions
WP673	ErbB Signaling Pathway
WP51	Regulation of Actin Cytoskeleton

目标的蛋白质ID

标题	内容
TARGETID	T59328
UNIPROID	EGFR_HUMAN
TARGNAME	Epidermal growth factor receptor (EGFR)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Epidermal growth factor receptor (EGFR)	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA

标题

内容

Epidermal growth factor receptor (EGFR)

MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA

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