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靶点信息46(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Activation B7-1 antigen (CD80)
TARGTYPE
Successful target
SYNONYMS
T-lymphocyte activation antigen CD80; LAB7; CTLA-4 counter-receptor B7.1; CD28LG1; CD28LG; BB1; B7
FUNCTION
T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. Involved in the costimulatory signal essential for T-lymphocyte activation.
SEQUENCE
MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
DRUGINFO
CAR-T cells targeting CD80/86
KEGGPATH
hsa04514:Cell adhesion molecules (CAMs)
KEGGPATH
hsa04620:Toll-like receptor signaling pathway
KEGGPATH
hsa04672:Intestinal immune network for IgA production
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04514 |
|
| hsa04620 |
|
| hsa04672 |
|
| hsa04940 |
|
| hsa05320 |
|
| hsa05322 |
|
| hsa05323 |
|
| hsa05330 |
|
| hsa05332 |
|
| hsa05416 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP75 |
|
| WP453 |
|
| WP2653 |
|
| WP2572 |
|
| WP2328 |
|
| WP1799 |
|
| WP1449 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Activation B7-1 antigen (CD80) |
|