靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP382:MAPK Signaling Pathway

WIKIPATH

WP384:Apoptosis Modulation by HSP70

WIKIPATH

WP706:SIDS Susceptibility Pathways

WIKIPATH

WP707:DNA Damage Response

REACPATH

R-HSA-111463:SMAC binds to IAPs

REACPATH

R-HSA-111464:SMAC-mediated dissociation of IAP:caspase complexes

REACPATH

R-HSA-111465:Apoptotic cleavage of cellular proteins

REACPATH

R-HSA-1474228:Degradation of the extracellular matrix

REACPATH

R-HSA-205025:NADE modulates death signalling

REACPATH

R-HSA-211227:Activation of DNA fragmentation factor

REACPATH

R-HSA-264870:Caspase-mediated cleavage of cytoskeletal proteins

NET_PATH

NetPath_11:TCR Signaling Pathway

NET_PATH

NetPath_14:IL2 Signaling Pathway

NET_PATH

NetPath_16:IL4 Signaling Pathway

INTEPATH

ajdiss_2pathway:Posttranslational regulation of adherens junction stability and dissassembly

INTEPATH

caspase_pathway:Caspase Cascade in Apoptosis

INTEPATH

faspathway:FAS (CD95) signaling pathway

INTEPATH

hivnefpathway:HIV-1 Nef: Negative effector of Fas and TNF-alpha

INTEPATH

lysophospholipid_pathway:LPA receptor mediated events

INTEPATH

nfat_3pathway:Role of Calcineurin-dependent NFAT signaling in lymphocytes

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04115	p53 signaling pathway
hsa04210	Apoptosis
hsa04650	Natural killer cell mediated cytotoxicity
hsa04668	TNF signaling pathway
hsa04726	Serotonergic synapse
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05010	Alzheimer's disease
hsa05012	Parkinson's disease
hsa05014	Amyotrophic lateral sclerosis (ALS)
hsa05016	Huntington's disease
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05133	Pertussis
hsa05134	Legionellosis
hsa05145	Toxoplasmosis
hsa05146	Amoebiasis
hsa05152	Tuberculosis
hsa05161	Hepatitis B
hsa05168	Herpes simplex infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05210	Colorectal cancer
hsa05416	Viral myocarditis

目标的 Wiki 路径数据

标题	内容
WP707	DNA Damage Response
WP706	SIDS Susceptibility Pathways
WP384	Apoptosis Modulation by HSP70
WP382	MAPK Signaling Pathway
WP3286	Copper homeostasis
WP314	FAS pathway and Stress induction of HSP regulation
WP2714	Signaling by Hippo
WP254	Apoptosis
WP2447	Amyotrophic lateral sclerosis (ALS)
WP2431	Spinal Cord Injury
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2371	Parkinsons Disease Pathway
WP2355	Corticotropin-releasing hormone
WP2328	Allograft Rejection
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP2263	Prostate Cancer
WP2059	Alzheimers Disease
WP2036	TWEAK Signaling Pathway
WP1984	Integrated Breast Cancer Pathway
WP1976	Signalling by NGF
WP1971	Integrated Cancer pathway
WP1896	Regulation of Apoptosis
WP1841	Intrinsic Pathway for Apoptosis
WP1784	Apoptotic execution phase
WP1772	Apoptosis Modulation and Signaling
WP1530	miRNA Regulation of DNA Damage Response

目标的蛋白质ID

标题	内容
TARGETID	T57943
UNIPROID	CASP3_HUMAN
TARGNAME	Caspase-3 (CASP3)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Caspase-3 (CASP3)	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH

最新招商产品更多>>