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靶点信息

标题

内容

相关药物

状态

TARGETID

T55860

FORMERID

TTDI02194

UNIPROID

TNFL4_HUMAN

TARGNAME

TAX transcriptionally-activated glycoprotein 1 (OX40)

GENENAME

TNFSF4

TARGTYPE

Clinical trial target

SYNONYMS

Tumor necrosis factor ligand superfamily member 4; TNFSF4; OX40L; Glycoprotein Gp34; CD252

FUNCTION

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

PDBSTRUC

2HEV

BIOCLASS

Cytokine: tumor necrosis factor

SEQUENCE

MERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL

DRUGINFO

AMG 386

DRUGINFO

RG7888

DRUGINFO

MEDI6383

DRUGINFO

mRNA-2416

DRUGINFO

mRNA-2752

KEGGPATH

hsa04060:Cytokine-cytokine receptor interaction

WIKIPATH

WP2203:TSLP Signaling Pathway

WIKIPATH

WP2877:Vitamin D Receptor Pathway

REACPATH

R-HSA-5669034:TNFs bind their physiological receptors

目标的 KEGG 通路数据

标题	内容
hsa04060	Cytokine-cytokine receptor interaction

目标的 Wiki 路径数据

标题	内容
WP2877	Vitamin D Receptor Pathway
WP2203	TSLP Signaling Pathway

目标的蛋白质ID

标题	内容
TARGETID	T55860
UNIPROID	TNFL4_HUMAN
TARGNAME	TAX transcriptionally-activated glycoprotein 1 (OX40)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
TAX transcriptionally-activated glycoprotein 1 (OX40)	MERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL

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