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靶点信息19(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
MHC class I NK cell receptor 2DL3 (CD158b2)
TARGTYPE
Clinical trial target
SYNONYMS
p58.2 MHC class-I-specific NK receptor; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; Natural killer-associated transcript 2; NKAT2b; NKAT2a; NKAT2; NKAT-2; Killer inhibitory receptor cl 2-3; Killer cell immunoglobulin-like receptor 2DL3; KIRCL23; KIR-023GB; CD158B2; CD158 antigen-like family member B2
FUNCTION
Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
SEQUENCE
MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
KEGGPATH
hsa04612:Antigen processing and presentation
KEGGPATH
hsa04650:Natural killer cell mediated cytotoxicity
KEGGPATH
hsa05332:Graft-versus-host disease
WIKIPATH
WP1829:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACPATH
R-HSA-198933:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04612 |
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| hsa04650 |
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| hsa05332 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| MHC class I NK cell receptor 2DL3 (CD158b2) |
|