靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP481:Insulin Signaling

WIKIPATH

WP536:Calcium Regulation in the Cardiac Cell

REACPATH

R-HSA-114516:Disinhibition of SNARE formation

REACPATH

R-HSA-1169091:Activation of NF-kappaB in B cells

REACPATH

R-HSA-416993:Trafficking of GluR2-containing AMPA receptors

REACPATH

R-HSA-418597:G alpha (z) signalling events

REACPATH

R-HSA-4419969:Depolymerisation of the Nuclear Lamina

REACPATH

R-HSA-5099900:WNT5A-dependent internalization of FZD4

REACPATH

R-HSA-5218921:VEGFR2 mediated cell proliferation

REACPATH

R-HSA-76005:Response to elevated platelet cytosolic Ca2+

NET_PATH

NetPath_14:IL2 Signaling Pathway

INTEPATH

cd8tcrdownstreampathway:Downstream signaling in naïve CD8+ T cells

INTEPATH

cd8tcrpathway:TCR signaling in naïve CD8+ T cells

INTEPATH

fcer1pathway:Fc-epsilon receptor I signaling in mast cells

INTEPATH

il2_1pathway:IL2-mediated signaling events

INTEPATH

ras_pathway:Regulation of Ras family activation

INTEPATH

tcr_pathway:TCR signaling in naïve CD4+ T cells

INTEPATH

tcrjnkpathway:JNK signaling in the CD4+ TCR pathway

INTEPATH

tcrraspathway:Ras signaling in the CD4+ TCR pathway

PANTPATH

P00003:Alzheimer disease-amyloid secretase pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04020	Calcium signaling pathway
hsa04062	Chemokine signaling pathway
hsa04064	NF-kappa B signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04070	Phosphatidylinositol signaling system
hsa04071	Sphingolipid signaling pathway
hsa04150	mTOR signaling pathway
hsa04270	Vascular smooth muscle contraction
hsa04310	Wnt signaling pathway
hsa04370	VEGF signaling pathway
hsa04510	Focal adhesion
hsa04530	Tight junction
hsa04540	Gap junction
hsa04650	Natural killer cell mediated cytotoxicity
hsa04662	B cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis
hsa04670	Leukocyte transendothelial migration
hsa04713	Circadian entrainment
hsa04720	Long-term potentiation
hsa04723	Retrograde endocannabinoid signaling
hsa04724	Glutamatergic synapse
hsa04725	Cholinergic synapse
hsa04726	Serotonergic synapse
hsa04727	GABAergic synapse
hsa04728	Dopaminergic synapse
hsa04730	Long-term depression
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04911	Insulin secretion
hsa04912	GnRH signaling pathway
hsa04916	Melanogenesis
hsa04918	Thyroid hormone synthesis
hsa04919	Thyroid hormone signaling pathway
hsa04921	Oxytocin signaling pathway
hsa04960	Aldosterone-regulated sodium reabsorption
hsa04961	Endocrine and other factor-regulated calcium reabsorption
hsa04970	Salivary secretion
hsa04971	Gastric acid secretion
hsa04972	Pancreatic secretion
hsa04973	Carbohydrate digestion and absorption
hsa05031	Amphetamine addiction
hsa05032	Morphine addiction
hsa05110	Vibrio cholerae infection
hsa05140	Leishmaniasis
hsa05143	African trypanosomiasis
hsa05146	Amoebiasis
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05214	Glioma
hsa05223	Non-small cell lung cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP536	Calcium Regulation in the Cardiac Cell
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP428	Wnt Signaling Pathway
WP399	Wnt Signaling Pathway and Pluripotency
WP382	MAPK Signaling Pathway
WP363	Wnt Signaling Pathway Netpath
WP35	G Protein Signaling Pathways
WP304	Kit receptor signaling pathway
WP289	Myometrial Relaxation and Contraction Pathways
WP2746	Signaling by the B Cell Receptor (BCR)
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP23	B Cell Receptor Signaling Pathway
WP2261	Signaling Pathways in Glioblastoma
WP2012	miRs in Muscle Cell Differentiation
WP1903	Response to elevated platelet cytosolic Ca2+
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1528	Physiological and Pathological Hypertrophy of the Heart

目标的蛋白质ID

标题	内容
TARGETID	T40276
UNIPROID	KPCB_HUMAN
TARGNAME	Protein kinase C beta (PRKCB)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Protein kinase C beta (PRKCB)	MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV

标题

内容

Protein kinase C beta (PRKCB)

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