靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

INTEPATH

nfkappabcanonicalpathway:Canonical NF-kappaB pathway

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

INTEPATH

telomerasepathway:Regulation of Telomerase

INTEPATH

tnfpathway:TNF receptor signaling pathway

PANTPATH

P00006:Apoptosis signaling pathway

PANTPATH

P00053:T cell activation

目标的 KEGG 通路数据

标题	内容
hsa04071	Sphingolipid signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04210	Apoptosis
hsa04380	Osteoclast differentiation
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04623	Cytosolic DNA-sensing pathway
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04917	Prolactin signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05030	Cocaine addiction
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05134	Legionellosis
hsa05140	Leishmaniasis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05146	Amoebiasis
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05162	Measles
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05202	Transcriptional misregulation in cancer
hsa05203	Viral carcinogenesis
hsa05206	MicroRNAs in cancer
hsa05212	Pancreatic cancer
hsa05215	Prostate cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05222	Small cell lung cancer
hsa05321	Inflammatory bowel disease (IBD)
hsa04010	MAPK signaling pathway
hsa04014	Ras signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04064	NF-kappa B signaling pathway
hsa04066	HIF-1 signaling pathway

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP706	SIDS Susceptibility Pathways
WP69	TCR Signaling Pathway
WP61	Notch Signaling Pathway
WP560	TGF Beta Signaling Pathway
WP408	Oxidative Stress
WP395	IL-4 Signaling Pathway
WP384	Apoptosis Modulation by HSP70
WP382	MAPK Signaling Pathway
WP289	Myometrial Relaxation and Contraction Pathways
WP2865	IL1 and megakaryotyces in obesity
WP2864	Apoptosis-related network due to altered Notch3 in ovarian cancer
WP2840	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WP2839	Hair Follicle Development: Organogenesis (Part 2 of 3)
WP2804	Hair Follicle Development: Induction (Part 1 of 3)
WP28	Selenium Metabolism and Selenoproteins
WP2795	Cardiac Hypertrophic Response
WP2794	Cytosolic sensors of pathogen-associated DNA
WP2759	Fc epsilon receptor (FCERI) signaling
WP2751	Transcriptional Regulation of White Adipocyte Differentiation
WP2746	Signaling by the B Cell Receptor (BCR)
WP2656	TAK1 activates NFkB by phosphorylation and activation of IKKs complex
WP2637	Structural Pathway of Interleukin 1 (IL-1)
WP262	EBV LMP1 signaling
WP2586	Aryl Hydrocarbon Receptor
WP2583	T-Cell Receptor and Co-stimulatory Signaling
WP254	Apoptosis
WP2435	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2203	TSLP Signaling Pathway
WP2112	IL17 signaling pathway
WP2064	Neural Crest Differentiation
WP2036	TWEAK Signaling Pathway
WP2034	Leptin signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP1984	Integrated Breast Cancer Pathway
WP1976	Signalling by NGF
WP195	IL-1 signaling pathway
WP1927	TCR signaling
WP1904	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
WP1839	Interleukin-1 signaling
WP1838	Interleukin-1 processing
WP1772	Apoptosis Modulation and Signaling
WP176	Folate Metabolism
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1533	Vitamin B12 Metabolism
WP15	Selenium Micronutrient Network
WP1449	Regulation of toll-like receptor signaling pathway
WP1434	Osteopontin Signaling

目标的蛋白质ID

标题	内容
TARGETID	T40192
UNIPROID	NFKB1_HUMAN
TARGNAME	DNA-binding factor KBF1 (p105)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
DNA-binding factor KBF1 (p105)	MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI

标题

内容

DNA-binding factor KBF1 (p105)

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