靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP366:TGF beta Signaling Pathway

WIKIPATH

WP382:MAPK Signaling Pathway

WIKIPATH

WP437:EGF/EGFR Signaling Pathway

WIKIPATH

WP481:Insulin Signaling

WIKIPATH

WP673:ErbB Signaling Pathway

WIKIPATH

WP69:TCR Signaling Pathway

WIKIPATH

WP710:DNA Damage Response (only ATM dependent)

WIKIPATH

WP75:Toll-like receptor signaling pathway

WHIZPATH

PW000445:Intracellular Signalling Through Adenosine Receptor A2a and Adenosine

WHIZPATH

PW000446:Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

WHIZPATH

PW000453:Fc Epsilon Receptor I Signaling in Mast Cells

REACPATH

R-HSA-193648:NRAGE signals death through JNK

REACPATH

R-HSA-205043:NRIF signals cell death from the nucleus

REACPATH

R-HSA-2559580:Oxidative Stress Induced Senescence

REACPATH

R-HSA-2871796:FCERI mediated MAPK activation

REACPATH

R-HSA-376172:DSCAM interactions

REACPATH

R-HSA-450321:JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1

REACPATH

R-HSA-450341:Activation of the AP-1 family of transcription factors

REACPATH

R-HSA-5693565:Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks

NET_PATH

NetPath_17:IL5 Signaling Pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04024	cAMP signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04141	Protein processing in endoplasmic reticulum
hsa04310	Wnt signaling pathway
hsa04380	Osteoclast differentiation
hsa04510	Focal adhesion
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04723	Retrograde endocannabinoid signaling
hsa04728	Dopaminergic synapse
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04910	Insulin signaling pathway
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04917	Prolactin signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa04930	Type II diabetes mellitus
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05210	Colorectal cancer
hsa05212	Pancreatic cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP69	TCR Signaling Pathway
WP673	ErbB Signaling Pathway
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP382	MAPK Signaling Pathway
WP366	TGF beta Signaling Pathway
WP314	FAS pathway and Stress induction of HSP regulation
WP313	Signaling of Hepatocyte Growth Factor Receptor
WP304	Kit receptor signaling pathway
WP3	Transcriptional activation by NRF2
WP288	NLR Proteins
WP286	IL-3 Signaling Pathway
WP2795	Cardiac Hypertrophic Response
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2637	Structural Pathway of Interleukin 1 (IL-1)
WP262	EBV LMP1 signaling
WP2593	JAK/STAT
WP2526	PDGF Pathway
WP2513	Nanoparticle triggered regulated necrosis
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2263	Prostate Cancer
WP2203	TSLP Signaling Pathway
WP2036	TWEAK Signaling Pathway
WP2034	Leptin signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP1976	Signalling by NGF
WP195	IL-1 signaling pathway
WP1841	Intrinsic Pathway for Apoptosis
WP1808	DSCAM interactions
WP1772	Apoptosis Modulation and Signaling
WP1584	Type II diabetes mellitus
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1528	Physiological and Pathological Hypertrophy of the Heart
WP1449	Regulation of toll-like receptor signaling pathway
WP12	Osteoclast Signaling

目标的蛋白质ID

标题	内容
TARGETID	T40097
UNIPROID	MK08_HUMAN
TARGNAME	Stress-activated protein kinase JNK1 (JNK1)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Stress-activated protein kinase JNK1 (JNK1)	MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR

标题

内容

Stress-activated protein kinase JNK1 (JNK1)

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