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靶点信息

标题

内容

相关药物

状态

TARGETID

T36059

FORMERID

TTDS00189

UNIPROID

AA3R_HUMAN

TARGNAME

Adenosine A3 receptor (ADORA3)

GENENAME

ADORA3

TARGTYPE

Clinical trial target

SYNONYMS

Adenosine receptor A3A; Adenosine receptor A3; Adenosine 3 receptor; A3AR; A3 Adenosine receptor

FUNCTION

The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Isoform 2: Receptor for adenosine.

PDBSTRUC

1R7N; 1OEA

BIOCLASS

GPCR rhodopsin

SEQUENCE

MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE

DRUGINFO

IB-MECA

DRUGINFO

CF102

DRUGINFO

NITD609

DRUGINFO

Tonapofylline

DRUGINFO

SCH-442416

DRUGINFO

BEMESETRON

Discontinued in Phase 3

DRUGINFO

BAY 60-6583

DRUGINFO

CF502

DRUGINFO

CF602

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容
WP80	Nucleotide GPCRs
WP455	GPCRs, Class A Rhodopsin-like
WP117	GPCRs, Other

目标的蛋白质ID

标题	内容
TARGETID	T36059
UNIPROID	AA3R_HUMAN
TARGNAME	Adenosine A3 receptor (ADORA3)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Adenosine A3 receptor (ADORA3)	MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE

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