靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP382:MAPK Signaling Pathway

WIKIPATH

WP422:MAPK Cascade

WIKIPATH

WP437:EGF/EGFR Signaling Pathway

WIKIPATH

WP51:Regulation of Actin Cytoskeleton

WIKIPATH

WP673:ErbB Signaling Pathway

WIKIPATH

WP710:DNA Damage Response (only ATM dependent)

WIKIPATH

WP732:Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

WHIZPATH

PW000453:Fc Epsilon Receptor I Signaling in Mast Cells

REACPATH

R-HSA-112412:SOS-mediated signalling

REACPATH

R-HSA-1169092:Activation of RAS in B cells

REACPATH

R-HSA-1236382:Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants

REACPATH

R-HSA-1250196:SHC1 events in ERBB2 signaling

REACPATH

R-HSA-1250347:SHC1 events in ERBB4 signaling

REACPATH

R-HSA-171007:p38MAPK events

REACPATH

R-HSA-179812:GRB2 events in EGFR signaling

REACPATH

R-HSA-180336:SHC1 events in EGFR signaling

REACPATH

R-HSA-1963640:GRB2 events in ERBB2 signaling

REACPATH

R-HSA-210993:Tie2 Signaling

REACPATH

R-HSA-2179392:EGFR Transactivation by Gastrin

REACPATH

R-HSA-2424491:DAP12 signaling

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04062	Chemokine signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04320	Dorso-ventral axis formation
hsa04360	Axon guidance
hsa04370	VEGF signaling pathway
hsa04530	Tight junction
hsa04540	Gap junction
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04650	Natural killer cell mediated cytotoxicity
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04720	Long-term potentiation
hsa04722	Neurotrophin signaling pathway
hsa04725	Cholinergic synapse
hsa04726	Serotonergic synapse
hsa04730	Long-term depression
hsa04810	Regulation of actin cytoskeleton
hsa04910	Insulin signaling pathway
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04915	Estrogen signaling pathway
hsa04916	Melanogenesis
hsa04917	Prolactin signaling pathway
hsa04919	Thyroid hormone signaling pathway
hsa04921	Oxytocin signaling pathway
hsa04960	Aldosterone-regulated sodium reabsorption
hsa05034	Alcoholism
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05166	HTLV-I infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05210	Colorectal cancer
hsa05211	Renal cell carcinoma
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05216	Thyroid cancer
hsa05218	Melanoma
hsa05219	Bladder cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05223	Non-small cell lung cancer
hsa05230	Central carbon metabolism in cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
WP710	DNA Damage Response (only ATM dependent)
WP673	ErbB Signaling Pathway
WP51	Regulation of Actin Cytoskeleton
WP437	EGF/EGFR Signaling Pathway
WP422	MAPK Cascade
WP382	MAPK Signaling Pathway
WP35	G Protein Signaling Pathways
WP2870	Extracellular vesicle-mediated signaling in recipient cells
WP2781	Signaling by ERBB4
WP2780	Signaling by ERBB2
WP2759	Fc epsilon receptor (FCERI) signaling
WP2746	Signaling by the B Cell Receptor (BCR)
WP2735	RAF/MAP kinase cascade
WP2713	Signaling by SCF-KIT
WP2694	DAP12 interactions
WP2677	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
WP2664	Gastrin-CREB signalling pathway via PKC and MAPK
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2586	Aryl Hydrocarbon Receptor
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP231	TNF alpha Signaling Pathway
WP2290	RalA downstream regulated genes
WP2261	Signaling Pathways in Glioblastoma
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP2002	miR-targeted genes in epithelium - TarBase
WP1984	Integrated Breast Cancer Pathway
WP1916	Signaling by PDGF
WP1913	Signaling by Insulin receptor
WP1911	Signaling by FGFR
WP1910	Signaling by EGFR
WP1873	NGF signalling via TRKA from the plasma membrane
WP1866	NCAM signaling for neurite out-growth
WP1794	Cell surface interactions at the vascular wall
WP127	IL-5 Signaling Pathway

目标的蛋白质ID

标题	内容
TARGETID	T35474
UNIPROID	RASK_HUMAN
TARGNAME	KRAS messenger RNA (KRAS mRNA)
TARGTYPE	Research target

目标的序列数据

标题	内容
KRAS messenger RNA (KRAS mRNA)	MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM

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