靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

NET_PATH

NetPath_13:IL1 Signaling Pathway

NET_PATH

NetPath_14:IL2 Signaling Pathway

NET_PATH

NetPath_16:IL4 Signaling Pathway

NET_PATH

NetPath_17:IL5 Signaling Pathway

NET_PATH

NetPath_21:RANKL Signaling Pathway

NET_PATH

NetPath_22:Leptin Signaling Pathway

NET_PATH

NetPath_24:TSLP Signaling Pathway

NET_PATH

NetPath_26:TWEAK Signaling Pathway

NET_PATH

NetPath_7:TGF_beta_Receptor Signaling Pathway

NET_PATH

NetPath_9:TNFalpha Signaling Pathway

INTEPATH

amb2_neutrophils_pathway:amb2 Integrin signaling

INTEPATH

ap1_pathway:AP-1 transcription factor network

INTEPATH

atf2_pathway:ATF-2 transcription factor network

INTEPATH

fra_pathway:Validated transcriptional targets of AP1 family members Fra1 and Fra2

INTEPATH

il23pathway:IL23-mediated signaling events

INTEPATH

il27pathway:IL27-mediated signaling events

INTEPATH

il6_7pathway:IL6-mediated signaling events

INTEPATH

lysophospholipid_pathway:LPA receptor mediated events

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

INTEPATH

shp2_pathway:SHP2 signaling

目标的 KEGG 通路数据

标题	内容
hsa04060	Cytokine-cytokine receptor interaction
hsa04066	HIF-1 signaling pathway
hsa04068	FoxO signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04623	Cytosolic DNA-sensing pathway
hsa04630	Jak-STAT signaling pathway
hsa04640	Hematopoietic cell lineage
hsa04668	TNF signaling pathway
hsa04672	Intestinal immune network for IgA production
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05020	Prion diseases
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05134	Legionellosis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05143	African trypanosomiasis
hsa05144	Malaria
hsa05146	Amoebiasis
hsa05152	Tuberculosis
hsa05161	Hepatitis B
hsa05162	Measles
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05168	Herpes simplex infection
hsa05200	Pathways in cancer
hsa05202	Transcriptional misregulation in cancer
hsa05321	Inflammatory bowel disease (IBD)
hsa05323	Rheumatoid arthritis
hsa05332	Graft-versus-host disease
hsa05410	Hypertrophic cardiomyopathy (HCM)

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP706	SIDS Susceptibility Pathways
WP69	TCR Signaling Pathway
WP615	Senescence and Autophagy in Cancer
WP530	Cytokines and Inflammatory Response
WP364	IL-6 signaling pathway
WP289	Myometrial Relaxation and Contraction Pathways
WP2849	Hematopoietic Stem Cell Differentiation
WP2848	Differentiation Pathway
WP2704	Interleukin-6 signaling
WP2431	Spinal Cord Injury
WP236	Adipogenesis
WP231	TNF alpha Signaling Pathway
WP2203	TSLP Signaling Pathway
WP2036	TWEAK Signaling Pathway
WP176	Folate Metabolism
WP1533	Vitamin B12 Metabolism
WP15	Selenium Micronutrient Network
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T32578
UNIPROID	IL6_HUMAN
TARGNAME	Interleukin-6 (IL6)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Interleukin-6 (IL6)	MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

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