靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-3000171:Non-integrin membrane-ECM interactions

REACPATH

R-HSA-5654219:Phospholipase C-mediated cascade: FGFR1

REACPATH

R-HSA-5654221:Phospholipase C-mediated cascade

REACPATH

R-HSA-5654227:Phospholipase C-mediated cascade

REACPATH

R-HSA-5654228:Phospholipase C-mediated cascade

REACPATH

R-HSA-5654688:SHC-mediated cascade:FGFR1

REACPATH

R-HSA-5654689:PI-3K cascade:FGFR1

REACPATH

R-HSA-5654693:FRS-mediated FGFR1 signaling

REACPATH

R-HSA-5654695:PI-3K cascade:FGFR2

REACPATH

R-HSA-5654699:SHC-mediated cascade:FGFR2

REACPATH

R-HSA-5654700:FRS-mediated FGFR2 signaling

REACPATH

R-HSA-5654704:SHC-mediated cascade:FGFR3

REACPATH

R-HSA-5654706:FRS-mediated FGFR3 signaling

REACPATH

R-HSA-5654710:PI-3K cascade:FGFR3

REACPATH

R-HSA-5654712:FRS-mediated FGFR4 signaling

REACPATH

R-HSA-5654719:SHC-mediated cascade:FGFR4

REACPATH

R-HSA-5654720:PI-3K cascade:FGFR4

REACPATH

R-HSA-5654726:Negative regulation of FGFR1 signaling

REACPATH

R-HSA-5654727:Negative regulation of FGFR2 signaling

REACPATH

R-HSA-5654732:Negative regulation of FGFR3 signaling

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04810	Regulation of actin cytoskeleton
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05218	Melanoma

目标的 Wiki 路径数据

标题	内容
WP51	Regulation of Actin Cytoskeleton
WP474	Endochondral Ossification
WP2848	Differentiation Pathway
WP2795	Cardiac Hypertrophic Response
WP2787	Syndecan interactions
WP2703	Extracellular matrix organization
WP2677	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
WP2653	PIP3 activates AKT signaling
WP2406	Cardiac Progenitor Differentiation
WP2377	Integrated Pancreatic Cancer Pathway
WP2064	Neural Crest Differentiation
WP2006	miR-targeted genes in squamous cell - TarBase
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP1911	Signaling by FGFR
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1539	Angiogenesis

目标的蛋白质ID

标题	内容
TARGETID	T31621
UNIPROID	FGF2_HUMAN
TARGNAME	Fibroblast growth factor-2 (FGF2)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Fibroblast growth factor-2 (FGF2)	MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS

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