靶点信息22(本栏目收费,不能显示细节,电话13136136841)
靶点信息
标题
内容
相关药物
状态
TARGETID
T31230
FORMERID
TTDS00307
UNIPROID
FRDA_HELPY
TARGNAME
Bacterial Fumarate reductase flavoprotein (Bact frdA)
GENENAME
Bact frdA
TARGTYPE
Successful target
SYNONYMS
Fumarate reductase; FRDA
FUNCTION
Two distinct, membrane-bound, fad-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; The fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
BIOCLASS
CH-CH donor oxidoreductase
ECNUMBER
EC 1.3.5.4
SEQUENCE
MKITYCDALIIGGGLAGLRASIACKQKGLNTIVLSLVPVRRSHSAAAQGGMQASLANAKKSEGDNEDLHFLDTVKGSDWGCDQQVARMFVTTAPKAIRELASWGVPWTRIKKGDRPAVVNGEHVTITERDDRHGYILSRDFGGTKKWRTCFTADATGHTMLYAVANEALHHKVDIQDRKDMLAFIHHDNKCYGAVVRDLITGEISAYVSKGTLLATGGYGRVYKHTTNAVICDGAGAASALETGVAKLGNMEAVQFHPTALVPSGILMTEGCRGDGGVLRDKFGRRFMPAYEPEKKELASRDVVSRRILEHIQKGYGAKSPYGDHVWLDIAILGRNHVEKNLRDVRDIAMTFAGIDPADSKEQTKDNMQGVPANEPEYGQAMAKQKGWIPIKPMQHYSMGGVRTNPKGETHLKGLFCAGEAACWDLHGFNRLGGNSVSEAVVAGMIIGDYFASHCLEAQIEINTQKVEAFIKESQDYMHFLLHNEGKEDVYEIRERMKEVMDEKVGVFREGKRLEEALKELQELYARSKNICVKNKVLHNNPELEDAYRTKKMLKLALCITQGALLRTESRGAHTRIDYPKRDDEKWLNRTLASWPSAEQDMPTIEYEELDVMKMEISPDFRGYGKKGNFIPHPKKEERDAEILKTILELEKLGKDRIEVQHALMPFELQEKYKARNMRLEDEEVRARGEHLYSFNVHELLDQHNANLKGEHHE
DRUGINFO
Morantel tartrate
DRUGINFO
Oxantel pamoate
DRUGINFO
Thiabendazole
DRUGINFO
2,3-DIMETHYL-1,4-NAPHTHOQUINONE
DRUGINFO
2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL
DRUGINFO
2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE
DRUGINFO
Citraconic acid
DRUGINFO
Flavin-Adenine Dinucleotide
DRUGINFO
Fumarate
目标的 KEGG 通路数据
标题内容
目标的 Wiki 路径数据
标题内容
目标的蛋白质ID
标题内容
TARGETID
UNIPROID
TARGNAME
TARGTYPE
目标的序列数据
标题内容
Bacterial Fumarate reductase flavoprotein (Bact frdA)
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