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靶点信息11(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Leukemia inhibitory factor (LIF)
TARGTYPE
Clinical trial target
SYNONYMS
Melanoma-derived LPL inhibitor; MLPLI; HILDA; Emfilermin; Differentiation-stimulating factor; D factor
FUNCTION
Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. LIF has the capacity to induce terminal differentiation in leukemic cells.
PDBSTRUC
2Q7N; 1PVH; 1EMR
SEQUENCE
MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF
目标的蛋白质ID
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目标的序列数据
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| Leukemia inhibitory factor (LIF) |
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