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靶点信息27(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Alpha-1-antitrypsin (SERPINA1)
TARGTYPE
Successful target
SYNONYMS
SERPINA1; PRO0684/PRO2209; Alpha1-proteinase; Alpha-1-antiproteinase; Alpha-1 protease inhibitor
FUNCTION
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
PDBSTRUC
9API; 8API; 7API; 5NBV; 5NBU
SEQUENCE
MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
DRUGINFO
2-Sulfhydryl-Ethanol
KEGGPATH
hsa04610:Complement and coagulation cascades
WIKIPATH
WP2882:Nuclear Receptors Meta-Pathway
WIKIPATH
WP2884:NRF2 pathway
WIKIPATH
WP558:Complement and Coagulation Cascades
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Alpha-1-antitrypsin (SERPINA1) |
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