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靶点信息22(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Ileal sodium/bile acid cotransporter (SLC10A2)
TARGTYPE
Clinical trial target
SYNONYMS
Solute carrier family 10 member 2; Sodium/taurocholate cotransporting polypeptide, ileal; SLC10A2; Na(+)dependent ileal bile acid transporter; Ileal sodiumdependent bile acid transporter; Ileal Na(+)/bile acid cotransporter; ISBT; IBAT; Apical sodiumdependent bile acid transporter; ASBT
FUNCTION
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
SEQUENCE
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
DRUGINFO
Taurocholic Acid
DRUGINFO
1614235 + 2330672
KEGGPATH
hsa04976:Bile secretion
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Ileal sodium/bile acid cotransporter (SLC10A2) |
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