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靶点信息

标题

内容

相关药物

状态

TARGETID

T22583

FORMERID

TTDC00158

UNIPROID

SC5A4_HUMAN

TARGNAME

Sodium/glucose cotransporter 2 (SLC5A4)

GENENAME

SLC5A4

TARGTYPE

Clinical trial target

SYNONYMS

Sodium/glucose cotransporter 4; SLC5A4

FUNCTION

Sodium-dependent glucose transporter.

BIOCLASS

Solute:sodium symporter

SEQUENCE

MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA

DRUGINFO

RG7201

DRUGINFO

SaxaDapa FDC

DRUGINFO

Remogli ozin-etabonate

Phase 2

DRUGINFO

D0V4MB

Remogliflozin etabonate

Phase 2

DRUGINFO

D0U9TM

Ponalrestat

Discontinued in Phase 3

WIKIPATH

WP2884:NRF2 pathway

REACPATH

R-HSA-189200:Hexose transport

REACPATH

R-HSA-428808:Na+-dependent glucose transporters

REACPATH

R-HSA-429593:Inositol transporters

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容
WP2884	NRF2 pathway

目标的蛋白质ID

标题	内容
TARGETID	T22583
UNIPROID	SC5A4_HUMAN
TARGNAME	Sodium/glucose cotransporter 2 (SLC5A4)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Sodium/glucose cotransporter 2 (SLC5A4)	MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA

标题

内容

Sodium/glucose cotransporter 2 (SLC5A4)

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