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靶点信息27(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Immunoglobulin gamma Fc receptor IIA (FCGR2A)
TARGTYPE
Successful target
SYNONYMS
Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; FcRII-a; Fc-gamma-RIIa; Fc-gamma RII-a; FCGR2A1; FCG2A; CDw32 A; CD32 A
FUNCTION
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
PDBSTRUC
3RY6; 3RY5; 3RY4; 3D5O; 1H9V
SEQUENCE
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVNSNN
KEGGPATH
hsa04145:Phagosome
KEGGPATH
hsa04380:Osteoclast differentiation
KEGGPATH
hsa04611:Platelet activation
KEGGPATH
hsa04666:Fc gamma R-mediated phagocytosis
KEGGPATH
hsa05140:Leishmaniasis
KEGGPATH
hsa05150:Staphylococcus aureus infection
KEGGPATH
hsa05152:Tuberculosis
KEGGPATH
hsa05322:Systemic lupus erythematosus
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04145 |
|
| hsa04380 |
|
| hsa04611 |
|
| hsa04666 |
|
| hsa05140 |
|
| hsa05150 |
|
| hsa05152 |
|
| hsa05322 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Immunoglobulin gamma Fc receptor IIA (FCGR2A) |
|