靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP69:TCR Signaling Pathway

WIKIPATH

WP722:Serotonin HTR1 Group and FOS Pathway

WHIZPATH

PW000445:Intracellular Signalling Through Adenosine Receptor A2a and Adenosine

WHIZPATH

PW000446:Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

WHIZPATH

PW000454:Insulin Signalling

REACPATH

R-HSA-114604:GPVI-mediated activation cascade

REACPATH

R-HSA-1257604:PIP3 activates AKT signaling

REACPATH

R-HSA-165158:Activation of AKT2

REACPATH

R-HSA-2730905:Role of LAT2/NTAL/LAB on calcium mobilization

REACPATH

R-HSA-2871837:FCERI mediated NF-kB activation

REACPATH

R-HSA-354192:Integrin alphaIIb beta3 signaling

REACPATH

R-HSA-389357:CD28 dependent PI3K/Akt signaling

REACPATH

R-HSA-389513:CTLA4 inhibitory signaling

REACPATH

R-HSA-392451:G beta:gamma signalling through PI3Kgamma

REACPATH

R-HSA-5218920:VEGFR2 mediated vascular permeability

REACPATH

R-HSA-5218921:VEGFR2 mediated cell proliferation

REACPATH

R-HSA-5607764:CLEC7A (Dectin-1) signaling

REACPATH

R-HSA-5625740:RHO GTPases activate PKNs

REACPATH

R-HSA-5674400:Constitutive Signaling by AKT1 E17K in Cancer

INTEPATH

bcr_5pathway:BCR signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa03320	PPAR signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04150	mTOR signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04152	AMPK signaling pathway
hsa04510	Focal adhesion
hsa04660	T cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04910	Insulin signaling pathway
hsa04919	Thyroid hormone signaling pathway
hsa04960	Aldosterone-regulated sodium reabsorption
hsa05145	Toxoplasmosis
hsa05160	Hepatitis C
hsa05205	Proteoglycans in cancer
hsa05213	Endometrial cancer
hsa05215	Prostate cancer
hsa05223	Non-small cell lung cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP437	EGF/EGFR Signaling Pathway
WP306	Focal Adhesion
WP2795	Cardiac Hypertrophic Response
WP2759	Fc epsilon receptor (FCERI) signaling
WP2754	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP2677	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
WP2653	PIP3 activates AKT signaling
WP2380	BDNF signaling pathway
WP2332	Interleukin-11 Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2261	Signaling Pathways in Glioblastoma
WP2032	TSH signaling pathway
WP1927	TCR signaling
WP1913	Signaling by Insulin receptor
WP185	Integrin-mediated Cell Adhesion
WP1826	GPVI-mediated activation cascade
WP1824	GPCR downstream signaling
WP1799	Costimulation by the CD28 family
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP722	Serotonin HTR1 Group and FOS Pathway
WP69	TCR Signaling Pathway
WP481	Insulin Signaling

目标的蛋白质ID

标题	内容
TARGETID	T20891
UNIPROID	PDPK1_HUMAN
TARGNAME	Phosphoinositide dependent protein kinase-1 (PDPK1)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Phosphoinositide dependent protein kinase-1 (PDPK1)	MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ

标题

内容

Phosphoinositide dependent protein kinase-1 (PDPK1)

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