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靶点信息24(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
IDHC_HUMAN; IDHP_HUMAN; IDH3A_HUMAN; IDH3B_HUMAN; IDH3G_HUMAN
TARGNAME
Isocitrate dehydrogenase (IDH)
GENENAME
IDH1; IDH2; IDH3A; IDH3B; IDH3G
TARGTYPE
Successful target
SYNONYMS
Isocitrate dehydrogenase [NAD]
FUNCTION
It may tightly associate or interact with the pyruvate dehydrogenase complex. Plays a role in intermediary metabolism and energy production.
BIOCLASS
CH-OH donor oxidoreductase
SEQUENCE
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
DRUGINFO
ENASIDENIB MESYLATE
KEGGPATH
hsa00020:Citrate cycle (TCA cycle)
KEGGPATH
hsa00480:Glutathione metabolism
KEGGPATH
hsa01100:Metabolic pathways
KEGGPATH
hsa01130:Biosynthesis of antibiotics
KEGGPATH
hsa01200:Carbon metabolism
KEGGPATH
hsa01210:2-Oxocarboxylic acid metabolism
KEGGPATH
hsa01230:Biosynthesis of amino acids
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00020 |
|
| hsa00480 |
|
| hsa01100 |
|
| hsa01130 |
|
| hsa01200 |
|
| hsa01210 |
|
| hsa01230 |
|
| hsa04146 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Isocitrate dehydrogenase (IDH) |
|