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靶点信息29(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin 2 receptor (IL2R)
SYNONYMS
p64; gammaC; Interleukin2 receptor subunit gamma; Interleukin-2 receptor subunit gamma; IL2R subunit gamma; IL2 receptor subunit gamma; IL-2RG; IL-2R subunit gamma; IL-2R; IL-2 receptor subunit gamma; Cytokine receptor common subunit gamma; CD132
FUNCTION
Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. Common subunit for the receptors for a variety of interleukins.
BIOCLASS
Cytokine receptor
DRUGINFO
Denileukin diftitox
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04144:Endocytosis
KEGGPATH
hsa04151:PI3K-Akt signaling pathway
KEGGPATH
hsa04630:Jak-STAT signaling pathway
KEGGPATH
hsa04640:Hematopoietic cell lineage
KEGGPATH
hsa05162:Measles
KEGGPATH
hsa05166:HTLV-I infection
WIKIPATH
WP1840:Interleukin-3, 5 and GM-CSF signaling
WIKIPATH
WP205:IL-7 Signaling Pathway
WIKIPATH
WP2203:TSLP Signaling Pathway
WIKIPATH
WP2328:Allograft Rejection
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04144 |
|
| hsa04151 |
|
| hsa04630 |
|
| hsa04640 |
|
| hsa05162 |
|
| hsa05166 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP49 |
|
| WP453 |
|
| WP2732 |
|
| WP2328 |
|
| WP2203 |
|
| WP205 |
|
| WP1840 |
|