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靶点信息39(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
M-phase inducer phosphatase 3 (MPIP3)
TARGTYPE
Literature-reported target
SYNONYMS
Dual specificity phosphatase Cdc25C; Cdc25C phosphatase
FUNCTION
Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. Functions as a dosage-dependent inducer in mitotic control.
PDBSTRUC
5M37; 5M36; 5M35; 3OP3; 3BZI
BIOCLASS
Phosphoric monoester hydrolase
SEQUENCE
MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
KEGGPATH
hsa04110:Cell cycle
KEGGPATH
hsa04114:Oocyte meiosis
KEGGPATH
hsa04914:Progesterone-mediated oocyte maturation
KEGGPATH
hsa05206:MicroRNAs in cancer
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04110 |
|
| hsa04114 |
|
| hsa04914 |
|
| hsa05206 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP707 |
|
| WP2516 |
|
| WP2377 |
|
| WP1859 |
|
| WP179 |
|
| WP1775 |
|
| WP1530 |
|
| WP727 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| M-phase inducer phosphatase 3 (MPIP3) |
|