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靶点信息70(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Prostaglandin E2 receptor EP4 (PTGER4)
TARGTYPE
Clinical trial target
SYNONYMS
Prostanoid EP4 receptor; Prostaglandin E2 receptor EP4 subtype; PTGER2; PGE2 receptor EP4 subtype; PGE receptor EP4 subtype
FUNCTION
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
SEQUENCE
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
DRUGINFO
16,16-dimethyl-PGE2
DRUGINFO
RQ-00000007 (oral)
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04080 |
|
| hsa04750 |
|
| hsa04924 |
|
| hsa05200 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP1825 |
|
| WP1824 |
|
| WP98 |
|
| WP455 |
|
| WP2877 |
|
| WP247 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Prostaglandin E2 receptor EP4 (PTGER4) |
|