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靶点信息23(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Factor XI messenger RNA (F11 mRNA)
TARGTYPE
Clinical trial target
SYNONYMS
Plasma thromboplastin antecedent (mRNA); PTA (mRNA); FXI (mRNA); Coagulation factor XI (mRNA)
FUNCTION
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
PDBSTRUC
6R8X; 6I58; 6C0S; 6AOD; 5WB6
SEQUENCE
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
DRUGINFO
alpha-ketothiazole analogue 36
KEGGPATH
hsa04610:Complement and coagulation cascades
WIKIPATH
WP1818:Formation of Fibrin Clot (Clotting Cascade)
WIKIPATH
WP272:Blood Clotting Cascade
目标的蛋白质ID
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目标的序列数据
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| Factor XI messenger RNA (F11 mRNA) |
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