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靶点信息13(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
TWIK-related acid-sensitive potassium channel 1 (TASK1)
TARGTYPE
Clinical trial target
SYNONYMS
Two pore potassium channel KT3.1; Two pore K(+) channel KT3.1; TWIK-related acid-sensitive K(+) channel 1; Acid-sensitive potassium channel protein TASK-1
FUNCTION
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
SEQUENCE
MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
KEGGPATH
hsa04925:Aldosterone synthesis and secretion
KEGGPATH
hsa04927:Cortisol synthesis and secretion
KEGGPATH
hsa04934:Cushing syndrome
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04925 |
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| hsa04927 |
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| hsa04934 |
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目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| TWIK-related acid-sensitive potassium channel 1 (TASK1) |
|