靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-416993:Trafficking of GluR2-containing AMPA receptors

REACPATH

R-HSA-418597:G alpha (z) signalling events

REACPATH

R-HSA-4419969:Depolymerisation of the Nuclear Lamina

REACPATH

R-HSA-450520:HuR (ELAVL1) binds and stabilizes mRNA

REACPATH

R-HSA-5099900:WNT5A-dependent internalization of FZD4

REACPATH

R-HSA-5218921:VEGFR2 mediated cell proliferation

REACPATH

R-HSA-76005:Response to elevated platelet cytosolic Ca2+

NET_PATH

NetPath_14:IL2 Signaling Pathway

INTEPATH

a6b1_a6b4_integrin_pathway:a6b1 and a6b4 Integrin signaling

INTEPATH

atf2_pathway:ATF-2 transcription factor network

INTEPATH

cd8tcrdownstreampathway:Downstream signaling in naïve CD8+ T cells

INTEPATH

cd8tcrpathway:TCR signaling in naïve CD8+ T cells

INTEPATH

endothelinpathway:Endothelins

INTEPATH

erbb1_downstream_pathway:ErbB1 downstream signaling

INTEPATH

il8cxcr1_pathway:IL8- and CXCR1-mediated signaling events

INTEPATH

il8cxcr2_pathway:IL8- and CXCR2-mediated signaling events

INTEPATH

mtor_4pathway:mTOR signaling pathway

INTEPATH

nfat_3pathway:Role of Calcineurin-dependent NFAT signaling in lymphocytes

INTEPATH

nfkappabcanonicalpathway:Canonical NF-kappaB pathway

INTEPATH

pdgfrbpathway:PDGFR-beta signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04723	Retrograde endocannabinoid signaling
hsa04724	Glutamatergic synapse
hsa04725	Cholinergic synapse
hsa04726	Serotonergic synapse
hsa04727	GABAergic synapse
hsa04728	Dopaminergic synapse
hsa04730	Long-term depression
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04911	Insulin secretion
hsa04912	GnRH signaling pathway
hsa04916	Melanogenesis
hsa04918	Thyroid hormone synthesis
hsa04919	Thyroid hormone signaling pathway
hsa04921	Oxytocin signaling pathway
hsa04960	Aldosterone-regulated sodium reabsorption
hsa04961	Endocrine and other factor-regulated calcium reabsorption
hsa04970	Salivary secretion
hsa04971	Gastric acid secretion
hsa04972	Pancreatic secretion
hsa05031	Amphetamine addiction
hsa05032	Morphine addiction
hsa05110	Vibrio cholerae infection
hsa05130	Pathogenic Escherichia coli infection
hsa05143	African trypanosomiasis
hsa05146	Amoebiasis
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05214	Glioma
hsa05223	Non-small cell lung cancer
hsa05231	Choline metabolism in cancer
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04020	Calcium signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04070	Phosphatidylinositol signaling system
hsa04071	Sphingolipid signaling pathway
hsa04150	mTOR signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04261	Adrenergic signaling in cardiomyocytes
hsa04270	Vascular smooth muscle contraction
hsa04310	Wnt signaling pathway
hsa04370	VEGF signaling pathway
hsa04510	Focal adhesion
hsa04530	Tight junction
hsa04540	Gap junction
hsa04650	Natural killer cell mediated cytotoxicity
hsa04664	Fc epsilon RI signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis
hsa04670	Leukocyte transendothelial migration
hsa04713	Circadian entrainment
hsa04720	Long-term potentiation

目标的 Wiki 路径数据

标题	内容
WP2012	miRs in Muscle Cell Differentiation
WP1978	Opioid Signalling
WP1903	Response to elevated platelet cytosolic Ca2+
WP1831	Integration of energy metabolism
WP1471	TOR Signaling
WP673	ErbB Signaling Pathway
WP536	Calcium Regulation in the Cardiac Cell
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP428	Wnt Signaling Pathway
WP399	Wnt Signaling Pathway and Pluripotency
WP363	Wnt Signaling Pathway Netpath
WP35	G Protein Signaling Pathways
WP304	Kit receptor signaling pathway
WP3	Transcriptional activation by NRF2
WP289	Myometrial Relaxation and Contraction Pathways
WP2806	Human Complement System
WP2795	Cardiac Hypertrophic Response
WP2787	Syndecan interactions
WP2733	Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
WP2713	Signaling by SCF-KIT
WP2688	DAG and IP3 signaling
WP2664	Gastrin-CREB signalling pathway via PKC and MAPK
WP2583	T-Cell Receptor and Co-stimulatory Signaling
WP244	Alpha 6 Beta 4 signaling pathway
WP2431	Spinal Cord Injury
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP2272	Pathogenic Escherichia coli infection
WP2261	Signaling Pathways in Glioblastoma
WP2197	Endothelin Pathways
WP2038	Regulation of Microtubule Cytoskeleton
WP2035	FSH signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T12808
UNIPROID	KPCA_HUMAN
TARGNAME	Protein kinase C alpha (PRKCA)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Protein kinase C alpha (PRKCA)	MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV

标题

内容

Protein kinase C alpha (PRKCA)

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