靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-1912408:Pre-NOTCH Transcription and Translation

REACPATH

R-HSA-3214858:RMTs methylate histone arginines

REACPATH

R-HSA-69229:Ubiquitin-dependent degradation of Cyclin D1

REACPATH

R-HSA-69231:Cyclin D associated events in G1

NET_PATH

NetPath_11:TCR Signaling Pathway

NET_PATH

NetPath_14:IL2 Signaling Pathway

NET_PATH

NetPath_3:Notch Signaling Pathway

NET_PATH

NetPath_4:EGFR1 Signaling Pathway

NET_PATH

NetPath_7:TGF_beta_Receptor Signaling Pathway

NET_PATH

NetPath_8:Wnt Signaling Pathway

INTEPATH

ap1_pathway:AP-1 transcription factor network

INTEPATH

ar_pathway:Coregulation of Androgen receptor activity

INTEPATH

atf2_pathway:ATF-2 transcription factor network

INTEPATH

betacatenin_nuc_pathway:Regulation of nuclear beta catenin signaling and target gene transcription

INTEPATH

cmyb_pathway:C-MYB transcription factor network

INTEPATH

ecadherin_nascentaj_pathway:E-cadherin signaling in the nascent adherens junction

INTEPATH

era_genomic_pathway:Validated nuclear estrogen receptor alpha network

INTEPATH

fak_pathway:Signaling events mediated by focal adhesion kinase

INTEPATH

foxm1pathway:FOXM1 transcription factor network

INTEPATH

fra_pathway:Validated transcriptional targets of AP1 family members Fra1 and Fra2

目标的 KEGG 通路数据

标题	内容
hsa04068	FoxO signaling pathway
hsa04110	Cell cycle
hsa04115	p53 signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04152	AMPK signaling pathway
hsa04310	Wnt signaling pathway
hsa04390	Hippo signaling pathway
hsa04510	Focal adhesion
hsa04630	Jak-STAT signaling pathway
hsa04917	Prolactin signaling pathway
hsa04919	Thyroid hormone signaling pathway
hsa04921	Oxytocin signaling pathway
hsa05161	Hepatitis B
hsa05162	Measles
hsa05166	HTLV-I infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05210	Colorectal cancer
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05216	Thyroid cancer
hsa05218	Melanoma
hsa05219	Bladder cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05222	Small cell lung cancer
hsa05223	Non-small cell lung cancer
hsa05416	Viral myocarditis

目标的 Wiki 路径数据

标题	内容
WP710	DNA Damage Response (only ATM dependent)
WP707	DNA Damage Response
WP61	Notch Signaling Pathway
WP45	G1 to S cell cycle control
WP399	Wnt Signaling Pathway and Pluripotency
WP366	TGF beta Signaling Pathway
WP363	Wnt Signaling Pathway Netpath
WP3286	Copper homeostasis
WP306	Focal Adhesion
WP2878	PPAR Alpha Pathway
WP2857	Mesodermal Commitment Pathway
WP2839	Hair Follicle Development: Organogenesis (Part 2 of 3)
WP2828	Bladder Cancer
WP2786	Pre-NOTCH Expression and Processing
WP2772	S Phase
WP2571	Polycystic Kidney Disease Pathway
WP2446	Retinoblastoma (RB) in Cancer
WP2431	Spinal Cord Injury
WP2377	Integrated Pancreatic Cancer Pathway
WP2263	Prostate Cancer
WP2261	Signaling Pathways in Glioblastoma
WP205	IL-7 Signaling Pathway
WP2034	Leptin signaling pathway
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP2002	miR-targeted genes in epithelium - TarBase
WP1984	Integrated Breast Cancer Pathway
WP1545	miRNAs involved in DNA damage response
WP1530	miRNA Regulation of DNA Damage Response
WP138	Androgen receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T12355
UNIPROID	CCND1_HUMAN
TARGNAME	G1/S-specific cyclin-D1 (CCND1)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
G1/S-specific cyclin-D1 (CCND1)	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI

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