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靶点信息45(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cyclic ADP-ribose hydrolase 1 (CD38)
TARGTYPE
Successful target
SYNONYMS
cADPr hydrolase 1; T10; Cyclic ADPribose hydrolase 1; ADPribosyl cyclase 1; ADPRC 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase
FUNCTION
Has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion.
PDBSTRUC
6EDR; 5F21; 5F1O; 5F1K; 4XJT
SEQUENCE
MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
DRUGINFO
4SCAR19 and 4SCAR38
DRUGINFO
Anti-CD38 CAR-T cells
DRUGINFO
CD38 and BCMA CAR-T Cells
DRUGINFO
CD38 CAR T cells
DRUGINFO
CD38-specific gene-engineered T cells
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00760 |
|
| hsa01100 |
|
| hsa04020 |
|
| hsa04640 |
|
| hsa04921 |
|
| hsa04970 |
|
| hsa04972 |
|
| hsa05169 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Cyclic ADP-ribose hydrolase 1 (CD38) |
|