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靶点信息53(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin 2 receptor alpha (IL2RA)
TARGTYPE
Successful target
SYNONYMS
TAC antigen; Interleukin-2 receptor subunit alpha; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha; IL-2 receptor alpha subunit; CD25 antigen; CD25
FUNCTION
The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. Receptor for interleukin-2.
PDBSTRUC
3NFP; 3IU3; 2ERJ; 2B5I; 1Z92
BIOCLASS
Cytokine receptor
SEQUENCE
MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQVAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04144:Endocytosis
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04144 |
|
| hsa04151 |
|
| hsa04630 |
|
| hsa04640 |
|
| hsa05162 |
|
| hsa05166 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP49 |
|
| WP453 |
|
| WP2732 |
|
| WP2328 |
|
| WP2203 |
|
| WP205 |
|
| WP1840 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Interleukin 2 receptor alpha (IL2RA) |
|