靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-1566977:Fibronectin matrix formation

REACPATH

R-HSA-198933:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

REACPATH

R-HSA-202733:Cell surface interactions at the vascular wall

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R-HSA-210991:Basigin interactions

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R-HSA-2129379:Molecules associated with elastic fibres

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R-HSA-216083:Integrin cell surface interactions

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R-HSA-3000157:Laminin interactions

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R-HSA-3000170:Syndecan interactions

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R-HSA-3000178:ECM proteoglycans

REACPATH

R-HSA-416700:Other semaphorin interactions

REACPATH

R-HSA-446343:Localization of the PINCH-ILK-PARVIN complex to focal adhesions

REACPATH

R-HSA-447041:CHL1 interactions

REACPATH

R-HSA-5663220:RHO GTPases Activate Formins

REACPATH

R-HSA-75892:Platelet Adhesion to exposed collagen

INTEPATH

a4b7_pathway:a4b7 Integrin signaling

INTEPATH

a6b1_a6b4_integrin_pathway:a6b1 and a6b4 Integrin signaling

INTEPATH

angiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling

INTEPATH

arf6_traffickingpathway:Arf6 trafficking events

INTEPATH

cxcr4_pathway:CXCR4-mediated signaling events

INTEPATH

fak_pathway:Signaling events mediated by focal adhesion kinase

目标的 KEGG 通路数据

标题	内容
hsa05222	Small cell lung cancer
hsa05410	Hypertrophic cardiomyopathy (HCM)
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414	Dilated cardiomyopathy
hsa04015	Rap1 signaling pathway
hsa04145	Phagosome
hsa04151	PI3K-Akt signaling pathway
hsa04360	Axon guidance
hsa04510	Focal adhesion
hsa04512	ECM-receptor interaction
hsa04514	Cell adhesion molecules (CAMs)
hsa04611	Platelet activation
hsa04670	Leukocyte transendothelial migration
hsa04810	Regulation of actin cytoskeleton
hsa05100	Bacterial invasion of epithelial cells
hsa05130	Pathogenic Escherichia coli infection
hsa05131	Shigellosis
hsa05133	Pertussis
hsa05140	Leishmaniasis
hsa05145	Toxoplasmosis
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer

目标的 Wiki 路径数据

标题	内容
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS
WP2272	Pathogenic Escherichia coli infection
WP2118	Arrhythmogenic Right Ventricular Cardiomyopathy
WP2064	Neural Crest Differentiation
WP1907	Semaphorin interactions
WP1883	Platelet Adhesion to exposed collagen
WP185	Integrin-mediated Cell Adhesion
WP1843	L1CAM interactions
WP1833	Integrin cell surface interactions
WP1829	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
WP1794	Cell surface interactions at the vascular wall
WP1793	Cell junction organization
WP366	TGF beta Signaling Pathway
WP313	Signaling of Hepatocyte Growth Factor Receptor
WP306	Focal Adhesion
WP2839	Hair Follicle Development: Organogenesis (Part 2 of 3)
WP2703	Extracellular matrix organization
WP2666	Elastic fibre formation
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2593	JAK/STAT

目标的蛋白质ID

标题	内容
TARGETID	T01851
UNIPROID	ITB1_HUMAN
TARGNAME	Integrin beta-1 (ITGB1)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Integrin beta-1 (ITGB1)	MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK

标题

内容

Integrin beta-1 (ITGB1)

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