靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-2871796:FCERI mediated MAPK activation

REACPATH

R-HSA-450321:JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1

REACPATH

R-HSA-450341:Activation of the AP-1 family of transcription factors

INTEPATH

cd40_pathway:CD40/CD40L signaling

INTEPATH

erbb2erbb3pathway:ErbB2/ErbB3 signaling events

INTEPATH

faspathway:FAS (CD95) signaling pathway

INTEPATH

foxopathway:FoxO family signaling

INTEPATH

nephrin_neph1_pathway:Nephrin/Neph1 signaling in the kidney podocyte

INTEPATH

p75ntrpathway:p75(NTR)-mediated signaling

INTEPATH

pdgfrbpathway:PDGFR-beta signaling pathway

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

INTEPATH

wnt_noncanonical_pathway:Noncanonical Wnt signaling pathway

PANTPATH

P00003:Alzheimer disease-amyloid secretase pathway

PANTPATH

P00006:Apoptosis signaling pathway

PANTPATH

P00010:B cell activation

PANTPATH

P00018:EGF receptor signaling pathway

PANTPATH

P00020:FAS signaling pathway

PANTPATH

P00021:FGF signaling pathway

PANTPATH

P00034:Integrin signalling pathway

PANTPATH

P00035:Interferon-gamma signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04024	cAMP signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04141	Protein processing in endoplasmic reticulum
hsa04310	Wnt signaling pathway
hsa04380	Osteoclast differentiation
hsa04510	Focal adhesion
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04723	Retrograde endocannabinoid signaling
hsa04728	Dopaminergic synapse
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04910	Insulin signaling pathway
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04917	Prolactin signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa04930	Type II diabetes mellitus
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05210	Colorectal cancer
hsa05212	Pancreatic cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP524	G13 Signaling Pathway
WP481	Insulin Signaling
WP428	Wnt Signaling Pathway
WP422	MAPK Cascade
WP408	Oxidative Stress
WP399	Wnt Signaling Pathway and Pluripotency
WP384	Apoptosis Modulation by HSP70
WP382	MAPK Signaling Pathway
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2637	Structural Pathway of Interleukin 1 (IL-1)
WP254	Apoptosis
WP2380	BDNF signaling pathway
WP185	Integrin-mediated Cell Adhesion
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T00663
UNIPROID	MK10_HUMAN
TARGNAME	Stress-activated protein kinase JNK3 (JNK3)
TARGTYPE	Patented target

目标的序列数据

标题	内容
Stress-activated protein kinase JNK3 (JNK3)	MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR

标题

内容

Stress-activated protein kinase JNK3 (JNK3)

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